Advances in Designing and Developing Vaccines, Drugs, and Therapies to Counter Ebola Virus
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چکیده
منابع مشابه
Virus-Vectored Ebola Vaccines
The Ebola virus disease (EVD) is one of the most dangerous infections affecting humans and animals. The first EVD outbreaks occurred in 1976 in Sudan and Zaire. Since then, more than 20 outbreaks have occurred; the largest of which (2014-2016) evolved into an epidemic in West Africa and claimed the lives of more than 11,000 people. Although vaccination is the most effective way to prevent epide...
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Zika virus (ZIKV) remained largely quiescent for nearly six decades after its first appearance in 1947. ZIKV reappeared after 2007, resulting in a declaration of an international "public health emergency" in 2016 by the World Health Organization (WHO). Until this time, ZIKV was considered to induce only mild illness, but it has now been established as the cause of severe clinical manifestations...
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Asefforts to successfully contain the largest outbreak of Ebola virus disease in history prove elusive, the mounting number of cases and deaths has brought research to developmuch-needed treatments andprotectivevaccines into the spotlight.Although theapprovalprocess for drugs and vaccines is typically slow and deliberate, the latestoutbreak,declaredby the World Health Organization (WHO) on Augu...
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In general, infertility is defined as the inability of couples to conceive after one year of unprotected sex. Causes of infertility can be related to both men and women. Unexplained infertility refers to the absence of a definable cause for a couplechr(chr('39')39chr('39'))s failure to achieve pregnancy, even after standard diagnostic methods including semen analysis, endometrial biopsy, etc. H...
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We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)-based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine. These findings demonstrate the utility of VSV-based vaccines against divergent viral pathogens, even when preexisting immunity to the vaccine vector is present.
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2018
ISSN: 1664-3224
DOI: 10.3389/fimmu.2018.01803